Charlie Chandler, 21, of Fitzwilliam Street, Bletchley, was charged on Thursday.
A 22-year-old man from Milton Keynes has also been arrested on suspicion of murder and attempted murder in connection with the attack.
He has not been named and remains in police custody.
Shortly before midnight on Saturday, Thames Valley Police were called to an address in Archford Croft, in the Emerson Valley area of the town.
Two 17-year-old boys, named as Dom Ansah and Ben Gillham-Rice, died after being knifed during an attack at a private house party.
Mr Chandler will appear at Milton Keynes Magistrates’ Court on Friday.
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